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Veterinary Snake Bite Treatment Reference (Pit Viper)

Pre-hospital advice, workup, antivenom indications, and treatment protocol for pit viper envenomation in dogs and cats.

Pre-hospital advice for owners

DoDon't
Keep pet calm and minimise movementDon't apply tourniquets
Carry to vehicle if possible (limit muscle activity)Don't apply ice or cut the wound
Transport immediately to nearest emergency vetDon't attempt to suck venom or capture the snake
Photograph the snake from a safe distance if possibleDon't give NSAIDs or other meds

Initial workup

TestWhy
Vital signs + serial physicalTrack progression of swelling, neuro signs
CBC (with platelet count)Pit viper bites cause thrombocytopenia, RBC echinocytosis
Coagulation (PT/aPTT, fibrinogen)Pit viper venom causes DIC-like coagulopathy
Chemistry + UABaseline organ function; CK rising = muscle damage
LactateMarker of perfusion and systemic toxicity

Treatment

TreatmentDetails
Antivenom (F(ab) or F(ab')2)1 vial IV diluted in 100-250 mL saline over 30-60 min. Repeat as clinically indicated.
IV fluidsCrystalloid replacement; aggressive resuscitation if shock
AnalgesiaOpioid (methadone 0.3 mg/kg IM). AVOID NSAIDs (coag risk).
AntibioticsBroad-spectrum if open wound; ampicillin/sulbactam reasonable empirical choice
Tetanus prophylaxisNot routinely needed
Wound careConservative - debride necrotic tissue once stable

When to use antivenom

IndicationNotes
Progressive swelling beyond initial bite areaStrongest indication
Coagulopathy (prolonged PT/aPTT, low fibrinogen)Antivenom can reverse if given early
ThrombocytopeniaHallmark of pit viper envenomation
Neurological signs (Mojave rattler, coral snake)Time-critical - antivenom should be given immediately
Cardiovascular instabilityIndicates systemic envenomation

Antivenom is most effective when given within 4-6 hours of envenomation but can still help up to 24 hours later. Monitor for delayed serum sickness 7-14 days after antivenom.

Frequently asked questions

Should owners apply a tourniquet to a snake bite?

No - tourniquets cause local tissue damage and don't prevent systemic venom spread. Keep the pet calm, transport quickly, and avoid suction, cutting or ice. The single best action is rapid transport.

When is antivenom indicated?

Progressive swelling beyond the bite, coagulopathy, thrombocytopenia, neurological signs (Mojave rattler, coral snake), or cardiovascular instability. Early administration (within 4-6 hours) is most effective but later doses can still help.

Do I need antibiotics for snake bites?

Routinely no for clean fang punctures. Indicated if there's significant tissue necrosis, secondary contamination, or open wounds. Broad-spectrum coverage (e.g. ampicillin/sulbactam) when needed.

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